Antagonist is the opposite of agonist. See also blocking agent. Medical Editor: Melissa Conrad Stöppler, MD; Antagonist: A substance that acts against and blocks an action. Antagonistic definition, acting in opposition; opposing, especially mutually. The antagonist muscle in a muscle set brings a limb or other anatomical part back to its initial position of rest. antagonist [an-tag´o-nist] antagonistic muscle. [1] Pleiotropy is the phenomenon where one gene controls for more than one phenotypic trait in an organism.. Antagonism can be competitive and reversible (i.e. Definition noun, plural: antagonists A biological structure or chemical agent that interferes with the physiological action of another Supplement Examples of antagonists are drugs that bind to cell receptors that prevent the agonists from eliciting a biological response. An antagonist muscle, just like the antagonist in a novel, works opposite to the main character, which in this case is the agonist muscle that undertakes the main action of movement. Antagonistic Relationships: The antagonistic relationships are manifested through parasitism, predation, competition and antibiosis between two different species. (see illustration.) An antagonistic pair of muscles do not actually cancel each other out, but they do work in opposites, hence the name. 1. a substance that tends to nullify the action of another, as a drug that binds to a cellular receptor for a hormone, neurotransmitter, or another drug blocking the action of that substance without producing any physiologic effect itself. They can be either of the same species (intraspecific interactions), or of different species (interspecific interactions). In ecology, a biological interaction is the effect that a pair of organisms living together in a community have on each other. Antagonist: when a drug antagonizes/prevents the effect of other drugs/ligands, but it is without activity. These effects may be short-term, like pollination and predation, or long-term; both often strongly influence the evolution of the species involved. Learn more. Antagonists and agonists are key players in the chemistry of the human body and in pharmacology. antagonistic definition: 1. actively opposing or showing unfriendliness towards something or someone: 2. actively opposing…. Find 8 ways to say ANTAGONISTIC, along with antonyms, related words, and example sentences at Thesaurus.com, the world's most trusted free thesaurus. Medical Definition of Antagonist. In biology, the term “antagonistic” means that one component cancels the effects of another, which is not literally true in this case. Other biological antagonists are muscles that occur in pairs. 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