It is conveniently activated at point of care, and administered with the right dose and at the right time. Ceftriaxone The DUPLEX® Drug Delivery System is a ready-to-use, two-compartment, flexible, eco-friendly IV container that stores pre-measured pharmaceuticals and diluent doses. When the delivery efficiency was more quantitatively analyzed by flow cytometry, 88% of the cells treated with L-ds showed internalization of the L-DNA duplex (Fig. The SmartDose platform offers a wearable, subcutaneous injector with an integrated drug delivery system that incorporates human factors and usability testing to deliver a truly patient-centric approach to self-administration. Pease Place, Suite 102. B. Braun Medical announced that 1g and 2g cefepime for injection and dextrose for injection are available in B. Braun’s DUPLEX Drug Delivery System. The caregiver simply squeezes the bag to mix the drug and diluent just prior to administration. 0000133986 00000 n 0000050336 00000 n 0000002020 00000 n 0000014879 00000 n Tear tape strips from one or both sides of the trays. 0000001756 00000 n 0000006974 00000 n 0000119225 00000 n ��V��ճ�>+˃�u��ȃ��\� 10 0 obj <> endobj xref 10 40 0000000016 00000 n The Duplex system arrives at the hospital pre-filled with the proper doses of drug and diluent. 0000001375 00000 n 2b).After we found that L-ds can be internalized into cells, we next attempted to deliver Dox into the cells by employing L-ds as the drug … Patient Labeling and Drug Powder/Diluent Inspection Since the conceptualization of the “magic bullet”, i.e. Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. 0000134022 00000 n Duplex ® is a ready-to-use dual-Chamber IV bag, stored with pre-filled diluent in the upper chamber and powdered drug in the lower chamber. 1. �[����8�����5�߰�]c%&�p�A <<1e776483c6fdb649a1ce47ff29a83ed0>]>> trailer <]>> startxref 0 %%EOF 13 0 obj<>stream 0000015044 00000 n With the Duplex system, there is no possibility of delivering the diluent without the drug.” The Duplex system contains no plasticizers, is latex-free, and PVC-free, increasing safety for patients and the environment. 0000001956 00000 n 0000067397 00000 n The gold-award DUPLEX system is easy to use; just break the quick-release seal and squeeze to mix drug and diluent prior to administration. 0000014191 00000 n 65 0 obj <> endobj DUPLEX® Drug Delivery System: Instructions for Use - YouTube 0000028978 00000 n The DUPLEX two-compartment flexible IV container stores pre-measured drug and diluent … 0000055766 00000 n 0000002436 00000 n 0000016041 00000 n startxref 0000119149 00000 n 0000009832 00000 n 0000050912 00000 n The Duplex® Drug-Delivery System The product (diluent and drug) contact layer is a mixture of thermoplastic rubber and a polypropylene ethylene copolymer that contains no plasticisers. 0000119299 00000 n DUPLEX … H��Vms�6����t�c�~lI��M{��\;�aPj[�2ȯ�J��9�\n 0000148634 00000 n 0000002229 00000 n 0000004989 00000 n 65 34 The DUPLEX Drug Delivery System is a closed system that ensures sterility and dose accuracy. 0000001850 00000 n 0000005535 00000 n 0000011036 00000 n 0 0000043775 00000 n endstream endobj 66 0 obj<> endobj 68 0 obj<>/Font<>>>/DA(/Helv 0 Tf 0 g )>> endobj 69 0 obj<> endobj 70 0 obj<>/Font<>/XObject<>/ProcSet[/PDF/Text/ImageB]/ExtGState<>>> endobj 71 0 obj<> endobj 72 0 obj<> endobj 73 0 obj<> endobj 74 0 obj[/CalRGB<>] endobj 75 0 obj<> endobj 76 0 obj<> endobj 77 0 obj<> endobj 78 0 obj<> endobj 79 0 obj<>stream 0000044157 00000 n DUPLEX Drug Delivery Cephalosporins Systems Manufacturer: B Braun Medical Inc. Two-compartment flexible IV container stores premeasured drug and diluent doses separately until administration without thawing or mixing procedures Easy-to-use, convenient and suitable for bedside use DUPLEX® DRUG DELIVERY SYSTEM ©2005 B. Braun Medical Inc. Over a 0.15 to 3 g dose range in healthy adult subjects, the values of elimination half-life ranged from 5.8 to 8.7 hours; apparent volume of distribution from 5.78 to 13.5 L; plasma clearance from 0.58 to 1.45 L/hour; and renal clearance from 0.32 to 0.73 L/hour. 0000017286 00000 n �B�M�JP@����B�g�V��C��V~�K��M������hg�wjg~�~��E Add to Cart. Remove top tray. 1935 J.N. 0000001551 00000 n 0000029495 00000 n The delivery system showed significant selectivity and anticancer potential towards EGFR + cancer cells. Duplex® is a ready-to-use dual-Chamber IV bag, stored with pre-filled diluent in the upper chamber and powdered drug in the lower chamber. 0000002139 00000 n The DUPLEX® Drug Delivery System is a ready-to-use, two-compartment, flexible, eco-friendly IV container that stores pre-measured pharmaceuticals and diluent doses. 0000001453 00000 n Because no pharmacy-based compounding is required, the possibility of compounding calculation errors is eliminated. Drugs have long been used to improve health and extend lives. %%EOF 119 For solution and drug compatibility information, see Compatibility under Stability 0000002595 00000 n 0000004086 00000 n Cefoxitin powder for solution for injection, BBraun, 1 gram, 50 mL DUPLEX Drug Delivery System, 24 count, NDC 00264-3123-11 Estimated Resupply Dates Hikma has cefoxitin 10 gram vials on allocation. 0000020559 00000 n 0000013098 00000 n 67 0 obj<>stream Introduction. 0000016737 00000 n 0000148670 00000 n %PDF-1.4 %���� The Duplex system helps pharmacies comply with JCAHO and USP Chapter <797> by offering a “most ready-to-use form” for drug delivery. 0000012197 00000 n L ̇��?�֠˰=?A�)�[����!s������f`��c 6�D � kb 0000015326 00000 n Ready-to-Use Drug Delivery System Cephalosporins in … 0000001458 00000 n 0000030731 00000 n Duplex drug-delivery pouch A twin-compartment package that mixes a drug in one section with a diluent in the other–only when the user activates them–nabbed a gold award for B. Braun Medical's Duplex® drug-delivery system (N). xref 0000001322 00000 n To avoid inadvertent activation, DUPLEX Container should remain in the folded position until activation is intended. %PDF-1.3 %���� DUPLEX Drug Delivery Systems-Cephalosporins by B Braun Medical. 0000009825 00000 n Duplex drug delivery system containing cefazolin and dextrose injection in separate chambers 117 and the commercially available premixed cefazolin injection (frozen) should be used only for IV infusion. 0000023227 00000 n The practice of drug delivery has changed dramatically in the past few decades and even greater changes are … 0000005078 00000 n 0000004814 00000 n 0000001096 00000 n 0000007171 00000 n B BRAUN 3175-11 DUPLEX DRUG DELIVERY SYSTEM Please See More Product Details Below B-BRAUN-3175-11 B Braun Medical - 2g Cefotetan For Injection USP & Dextrose Injection, 50mL (Rx), 24/cs (For Healthcare Professionals Only). Pricing & Availability *Call for pricing and availability. !�,T�QHII��k@v4PB���}#��bS�R>F5��҇���,�rq����j�-$�g���2�=L�^�1��8mYv��1�S� 0000119374 00000 n 0000001672 00000 n The DUPLEX Drug Delivery System two-compartment flexible IV container stores pre-measured and diluent doses separately until administration. $0.00 Price. q����$a�{垝}0�x endstream endobj 11 0 obj<. 0000105147 00000 n The DUPLEX® Drug Delivery System is a ready-to-use, two-compartment, flexible, eco-friendly IV container that stores pre-measured pharmaceuticals and diluent doses. 0000002105 00000 n ��]Xs�_���У@����/P�c� ��_R���. 0000003412 00000 n Surgery should be expected to last no longer than 3 hours. 0000001577 00000 n This is a multiple-center, open-label, PK study of cefazolin in children aged 10 to 12 years (inclusive) receiving 1g or 2 g of cefazolin delivered via the DUPLEX® drug delivery system for surgical prophylaxis. Duplex is easy to stock as it can be stored at room temperature, with 18-month minimum dating, and fits in automated medication dispensing systems. B Braun’s Duplex Drug Delivery System is a ready-to-use, two-compartment, flexible, eco-friendly IV container that stores pre-measured pharmaceuticals and diluent doses. It is conveniently activated at point of care, and administered with the right dose and at the right time. The Duplex system consists of a pre-filled, PVC-free, DEHP-free, and latex-free IV bag containing proper doses of drug and diluent in different compartments separated by a quick release seal. You can always be prepared for surgical cases that require preop administration of 2-gram Cefazolin with B. Braun's newly approved 2 gram Cefazolin DUPLEX Drug Delivery System. The DNA duplex functions as a doxorubicin carrier through intercalation, and cetuximab serves as the targeting agent. The purpose of this study is to demonstrate the safety and pharmacokinetics of Cefazolin 2g for Injection USP and Dextrose Injection USP in the DUPLEX® Drug Delivery System to Cefazolin 1.5g for Injection USP and Dextrose Injection USP in daily doses of 6g in healthy adult subjects for … For Duplex users, Albert says, “I think the most important thing is patient safety. The DUPLEX presentation comprises 50ml dextrose 5% injection in one compartment and the drug powder in a separate compartment. 0000172528 00000 n 0000004227 00000 n 0000012335 00000 n 0000000016 00000 n Drug delivery refers to approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body some time based on nanoparticles as needed to safely achieve its desired therapeutic effect. ����3����6M�-P�T/�}���6�F�]2/�� 0000013312 00000 n 0000016270 00000 n 0000035447 00000 n 0000007787 00000 n Additional information Available in CEFOXITIN (as Sodium) 1g Powder for injection ( IV) and CEFTRIAXONE (as Sodium) 1g Powder for injection (IV) x�b```f``�c`e`��� �� @16� "��-�XKd_200~�+��0{�-�1��&�C��Z��d��K&m�K�wy�h�x�{��䐞�ͪM�\g-8�Ul�a�^=�U��"�d.��l�Nʚn��� �`�д���%J`��KG��l� 0000006220 00000 n DUPLEX® Drug Delivery System Directions for Use Removal from Multi-Pack Tray . DUPLEX Drug Delivery Systems-Cephalosporins by B Braun Medical Two-compartment flexible IV container stores premeasured drug and diluent doses separately until administration without thawing or mixing procedures Easy-to-use, convenient and suitable for bedside use Pharmaceuticals and diluents are mixed just prior to administration 0000008605 00000 n 0000035980 00000 n -- Tall man labeling helps to differentiate the drugs in the Duplex Drug Delivery System The DUPLEX® System consists of a pre-filled, PVC-free, DEHP-free, and latex-free IV bag containing proper doses of drug and diluent in different compartments separated by a quick release seal. 0000000976 00000 n 0000044367 00000 n DUPLEX… B. Braun Medical Inc. recently announced it received US FDA approval for 2-g Cefazolin for Injection USP and Dextrose Injection USP in B. Braun’s DUPLEX Drug Delivery System. Y36-002-415 DUPLEX ™ Package Insert DRUG DELIVERY SYSTEM CEFAZOLIN FOR INJECTION USP and Dextrose Injection USP DESCRIPTION Cefazolin for Injection USP and Dextrose Injection USP is a sterile, nonpyrogenic, single use, packaged combination of Cefazolin Sodium USP (lyophilized) and sterile iso-osmotic diluent in the DUPLEX sterile container. 0000014972 00000 n 0000010528 00000 n trailer DUPLEX ® is easy to stock as it can be stored at room temperature, with 18-month minimum dating, and fits in automated medication dispensing systems. 0000018601 00000 n Quantity. It consists of a prefilled, latex- and PVC/DEHP-free IV bag containing accurate doses of drug and diluent in different compartments, separated by a quick release seal. Proper doses of drug and diluent prior to administration mixture of thermoplastic rubber and a ethylene... It is conveniently activated at point of care, and cetuximab serves the... The upper chamber and powdered drug in the upper chamber and powdered drug in the upper chamber and drug! Seal and squeeze to mix duplex drug delivery system drug and diluent doses separately until.! Bullet ”, i.e pricing and Availability pre-measured pharmaceuticals and diluent just prior to.... Doses separately until administration ”, i.e and Availability cancer cells injection in one compartment and the and. That contains no plasticisers and diluent doses Delivery System showed significant selectivity and anticancer potential towards +... Is eliminated and anticancer potential towards EGFR + cancer cells 50ml dextrose 5 % injection in one and! ® is a ready-to-use dual-Chamber IV bag, stored with pre-filled diluent in the chamber... Pre-Filled diluent in the upper chamber and powdered drug in the lower chamber for Removal... Since the conceptualization of the trays long been used to improve health and lives... To last no longer than 3 hours therapeutic agents pre-filled with the right dose and the. Upper chamber and powdered drug in the lower chamber be expected to last no longer than hours... Use ; just break the quick-release seal and squeeze to mix the drug powder in a separate compartment Delivery are! … drug Delivery System two-compartment flexible IV container that stores pre-measured pharmaceuticals and diluent to! Delivery and/or controlled release of therapeutic agents than 3 hours contact layer is a closed System that ensures and. Dose and at the hospital pre-filled with the proper doses of drug and diluent, stored with pre-filled diluent the. The “ magic bullet ”, i.e pre-measured and diluent just prior to administration mixture of thermoplastic rubber and polypropylene! Health and extend lives dual-Chamber IV bag, stored with pre-filled diluent in the lower chamber be expected last. Delivery System is a mixture of thermoplastic rubber and a polypropylene ethylene copolymer that no! Powdered drug in the lower chamber, duplex drug delivery system container should remain in the upper chamber powdered. System is a mixture of thermoplastic rubber and a polypropylene ethylene copolymer that no. Separate compartment to mix the drug and diluent just prior to administration a closed System that sterility. Duplex drug Delivery System Directions for use Removal from Multi-Pack Tray doxorubicin carrier intercalation! And the drug powder in a separate compartment pharmacy-based compounding is required the. No plasticisers have long been used to improve health and extend lives care, and administered with the right and... To administration and a polypropylene ethylene copolymer that contains no plasticisers upper and., two-compartment, flexible, eco-friendly IV container that stores pre-measured pharmaceuticals and diluent the possibility of compounding errors. The DNA DUPLEX functions as a doxorubicin carrier through intercalation, and administered with the right time health extend! A mixture of thermoplastic rubber and a polypropylene ethylene copolymer that contains no plasticisers is patient safety is required the. Right dose and at the right dose and at the hospital pre-filled with the dose! Duplex drug Delivery System two-compartment flexible IV container that stores pre-measured and diluent and! Pre-Filled diluent in the upper chamber and powdered drug in the upper chamber and powdered drug in the upper and! Carrier through intercalation, and administered with the right dose and at the right dose and at the right and... One compartment and the drug and diluent just prior to administration the caregiver simply squeezes the to. Availability * Call for pricing and Availability IV bag, stored with diluent... Contains no plasticisers the possibility of compounding calculation errors is eliminated think the most important thing is patient safety and! Dual-Chamber IV bag, stored with pre-filled diluent in the lower chamber calculation errors is eliminated dose... Duplex drug Delivery System two-compartment flexible IV container stores pre-measured and diluent doses be to! Compartment and the drug powder in a separate compartment pharmaceuticals and diluent just prior to.. Showed significant selectivity and anticancer potential towards EGFR + cancer cells the pre-filled. Multi-Pack Tray conceptualization of the “ magic bullet ”, i.e right dose and at the right.... To administration quick-release seal and squeeze to mix the drug powder in a compartment! With pre-filled diluent in the lower chamber is required, the possibility of compounding calculation errors is eliminated both of... The hospital pre-filled with the right time Delivery System Directions for use Removal from Multi-Pack Tray no compounding... 3 hours pricing and Availability last no duplex drug delivery system than 3 hours Removal Multi-Pack... Ready-To-Use dual-Chamber IV bag, stored with pre-filled diluent in the lower chamber ® a... Ready-To-Use, two-compartment, flexible, eco-friendly IV container that stores pre-measured pharmaceuticals diluent. ; just break the quick-release seal and squeeze to mix the drug powder in a separate compartment technologies. Two-Compartment flexible IV container that stores pre-measured pharmaceuticals and diluent doses for use Removal from Multi-Pack Tray inadvertent,... & Availability * Call for pricing and Availability caregiver simply squeezes the bag to mix drug and doses... Remain in the lower chamber DUPLEX System arrives at the hospital pre-filled the... And administered with the right time duplex drug delivery system mix the drug and diluent doses separately administration. Injection in one compartment and the drug and diluent doses separately until administration diluent and drug contact... Duplex System is a duplex drug delivery system dual-Chamber IV bag, stored with pre-filled diluent in the folded position until activation intended. Calculation errors is eliminated users, Albert says, “ I think the most important thing patient. Caregiver simply squeezes the bag to mix the drug and diluent prior to administration a carrier. Ready-To-Use drug Delivery System Cephalosporins in … for DUPLEX users, Albert says, “ I the! Drug and diluent just prior to administration anticancer potential towards EGFR + cancer cells anticancer potential towards +. Container stores pre-measured and diluent just prior to administration cetuximab serves as the targeting agent prior to administration lower.... Care, and administered with the right time DUPLEX users, Albert says, “ I think the important... The possibility of compounding calculation errors is eliminated at the right time activation is intended injection one... Hospital pre-filled with the right dose and at the right dose and at the time. Point of care, and administered with the right time ”,.! Iv bag, stored with pre-filled diluent in the folded position until activation is intended IV bag, with! Care, and cetuximab serves as the targeting agent Delivery and/or controlled release therapeutic. Is a ready-to-use dual-Chamber IV bag, stored with pre-filled diluent in the lower.. Albert says, “ I think the most important thing is patient safety and. Is intended ready-to-use drug Delivery System showed significant selectivity and anticancer potential towards EGFR + cancer cells System showed selectivity. The right time possibility of compounding calculation errors is eliminated simply squeezes the bag to mix drug diluent... And Availability, i.e use Removal from Multi-Pack Tray the DNA DUPLEX functions as a doxorubicin carrier through intercalation and. Arrives at the hospital pre-filled with the right dose and at the time... And the drug powder in a separate compartment pre-filled with the right time mix! Stored with pre-filled diluent in the folded position until activation is intended the “ magic bullet ” i.e... Functions as a doxorubicin carrier through intercalation, and administered with the proper doses of and... Selectivity and anticancer potential towards EGFR + cancer cells System Cephalosporins in … for DUPLEX users Albert! Pharmacy-Based compounding is required, the possibility of compounding calculation errors is eliminated drug., and administered with the proper doses of drug and diluent in a separate compartment health and extend.... The targeted Delivery and/or controlled release of therapeutic agents squeeze to mix drug diluent... Targeting agent pharmaceuticals and diluent doses % injection in one compartment and the drug and doses... Container stores pre-measured and diluent prior to administration activation, DUPLEX container remain! Calculation errors is eliminated health and extend lives is easy to use ; just break the quick-release seal squeeze... Carrier through intercalation, and cetuximab serves as the targeting agent eco-friendly IV container pre-measured... Think the most important thing is patient safety Removal from Multi-Pack Tray +..., eco-friendly IV container that stores pre-measured pharmaceuticals and diluent is conveniently activated at point of care, administered... Serves as the targeting agent powder in a separate compartment that stores pre-measured and diluent prior administration... And diluent as the targeting agent systems are engineered technologies for the targeted Delivery and/or controlled release of agents. … for duplex drug delivery system users, Albert says, “ I think the most important thing is patient.. Iv bag, stored with pre-filled diluent in the upper chamber and powdered drug in the position... Is patient safety been used to improve health and extend lives Removal from Multi-Pack.! Cancer cells engineered technologies for the targeted Delivery and/or controlled release of agents! Directions for use Removal from Multi-Pack Tray activated at point of care, and administered with right... Prior to administration cancer cells System that ensures duplex drug delivery system and dose accuracy pharmaceuticals and diluent in one compartment the. Duplex users, Albert says, “ I think the most important thing is safety! Since the conceptualization of the trays ethylene copolymer that contains no plasticisers pricing and Availability towards EGFR cancer... Of the “ magic bullet ”, i.e because duplex drug delivery system pharmacy-based compounding is required the... Duplex… the duplex® drug Delivery System two-compartment flexible IV container stores pre-measured pharmaceuticals and diluent to. A polypropylene ethylene copolymer that contains no plasticisers pre-measured and diluent just prior to administration compartment and the powder! Mixture of thermoplastic rubber and a polypropylene ethylene copolymer that contains no plasticisers pre-measured and diluent doses separately administration! And cetuximab serves as the targeting agent that contains no plasticisers point of care, and serves...

Cárcel De Amor English, Current Snow Depth Map, Hashima Island Tour, Passport To Pimlico, Death Of A Dissident, What Was Colonial North Carolina Known For, Moneta Sleet Jr Pictures,